Is
the best known and widely used, as a germicide, of all
the Quaternaries Ammonium, is referred in almost all pharmacopeias
and correspond to the generic chemical notation of "ALKYL
DIMETHYL BENZYL AMMONIUM CHLORIDE".
The BENZALKONIUM CHLORIDE, as generally mentioned, is
obtained, from high purity coconut oil fatty acid, following
strict specifications of the international pharmacopeia,
the alkyl radical representing the mix of C8 H17 up to
C18 H37.
In the coconut oil these fatty acids are present in a
Constant proportion, and the alkyl radical correspond
in the mix as containing approximately 67 % C12, 25 %
C14, 7% C16 e 1% DE C8 + C10 + C18. The Phenolic coefficient
for the Benzalkonium Chloride in pharmacopeias is STAPHILOCOCCUS
AUREOS, 275 and SALMONELA TYPHOSA, 250.
As new technology arrived, become possible distillate
and separate the coconut oil fatty acids and enrich the
mix with a higher percentage of C14, generally recognized
as having greater germicide action and hard water resistance.
APPLICATIONS
The
HESTERQUAT 3500-50 is utilized in topic use preparations
in the pharmaceutical, veterinary and cosmetic industries.
As a bactericide, is an active ingredient in formulations
for detergents - disinfectants, hospital and domestic
disinfectants, as well as in pool water and cooling towers
treatment.
COMPATIBILITY AND INCOMPATIBILITY
The
HESTERQUAT 3500-50 has a cationic positive electric
charge, is compatible with others cationic, Zwitterionic
(amphoteric) (within acidic pH), amine oxide and nonionic
detergents.
Is incompatible with anionic detergents, some salts
and soaps.
BIOLOGIC CHARACTERISTICS
The
oral toxicity of HESTERQUAT 3500-50 experimented in mice,
defined the following levels:
DL - 50 = 440 Mg / Kg DL - 100 = 650 Mg / Kg
SKIN IRRITATION AND SENSIBILITY
The
HESTERQUAT 3500-50 when used in a 1:1000 concentration
is not considered as a primary irritant or skin sensitive.
HANDLING HAZARD
The
HESTERQUAT 3500-50, in concentrated solution, is corrosive
and could be considered as a primary irritant.
MEDICAL
CARE: If swallowed, the patient should drink
enough water or milk and look for immediate medical
care. Skin contact: remove the clothes and wash first
with water, and immediately after with water and soap.
Eyes contact: wash with water for a minimum of 15 minutes
Look for medical assistance immediately.
NOTE:
The gastric wash is contraindicated, Should be taken
measures related with Circulatory shock, respiratory
depression and seizure (convulsion).
The information contained in this technical brochure,
is based on our best experience, and considered as correct;
however the Company shall not be liable whatsoever for
improper applications, or for any act which would infringe
a patent or proprietary interest.
